What’s the cost of a flight from Panama City to Madrid?

Prices vary based on date, airline, and availability. Compare several options if you're flying between Panama City and Madrid.

Choose a date to explore the best fares now.

If possible, avoid holiday periods: ticket prices tend to rise quickly and availability drops, especially on busy routes. Morning and evening flights are often in high demand too — book early to get a good fare.

Which airports are most convenient between Panama City and Madrid?

Whether it’s cost or connection time, the right airport combination can make a difference.

• Airports in Panama City: There are 2 airports in Panama City - Pacífico International Airport, Paitilla.
• Airports in Madrid: Madrid - Barajas is the only functioning airport for now.

In some cases, flying into a secondary airport can also reduce transfer costs. Connections from multiple airports give you more flight options and airlines.

Flight filters for the route Panama City – Madrid

Customize your search on Jetcost to focus only on flights that suit your needs. Whether you want a direct connection, specific airline, or shorter layover, filters help you find it faster.

Other popular destinations

Flights to Spain are often searched alongside: Alicante, Barcelona, Madrid, Málaga, Palma de Mallorca.

The cheapest flights might leave at odd hours or arrive at less central airports — keep that in mind. If you travel often, you can always select your trusted airlines from the available options.