Find out what a flight from San Francisco to Mytilene might cost

Prices vary based on date, airline, and availability. Compare several options if you're flying between San Francisco and Mytilene.

Select your dates to check current offers.

Try shifting your departure forward or backward by a day to find better options. If you’re looking for a good deal, consider flying outside peak hours as well.

Best airport options between San Francisco and Mytilene

If you're open to flying into or out of more than one airport, you’ll have more routes to compare.

• Airports in San Francisco: San Francisco is the only operating airport.
• Airports in Mytilene: Mytilene is the sole airport currently available.

Some airports offer extras like lounges, fast track, or self check-in — good to keep in mind. Comparing airports by services offered helps you balance cost and comfort.

Plan smarter: flights from San Francisco to Mytilene

Find the flight that fits your plans with Jetcost. You can filter results by stops, agencies, budget, time of day, and airline — all in one search.

Other popular destinations

Travelers flying to Greece also checked out: Athens, Crete, Kerkyra, Thessaloniki, Thira.

Comparing offers from multiple agencies helps you find the best price for the same route. You can also spot exclusive deals from individual airlines right in the results list.